Hiroyuki Ohshiro Selected Research

N- (2- hydroxyethyl)- N,2- dimethyl- 8- ((5- methyl- 3,4- dihydro- 2H- chromen- 4- yl)amino)imidazo(1,2- a)pyridine- 6- carboxamide

2/2009

N-(2-hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a novel, potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease.

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Hiroyuki Ohshiro Research Topics

Disease

1	Glucose Intolerance 12/2012
1	Gastroesophageal Reflux (GERD) 02/2009
1	Hyperalgesia 08/2007
1	Pain (Aches) 08/2007

Drug/Important Bio-Agent (IBA)

1	AcidsIBA 02/2009
1	Proton Pump InhibitorsIBA 02/2009
1	N- (2- hydroxyethyl)- N,2- dimethyl- 8- ((5- methyl- 3,4- dihydro- 2H- chromen- 4- yl)amino)imidazo(1,2- a)pyridine- 6- carboxamideIBA 02/2009
1	Histamine (Histamine Dihydrochloride)FDA Link 02/2009
1	pyridineIBA 02/2009
1	grapiprantIBA 08/2007
1	LigandsIBA 08/2007
1	Analgesics (Analgesic Drugs)IBA 08/2007
1	CarrageenanIBA 08/2007
1	Freund's AdjuvantIBA 08/2007
1	Prostaglandins EIBA 08/2007

Therapy/Procedure

2	Oral Administration 12/2012 - 08/2007
1	Therapeutics 02/2009